Clinical Trial Design Specialist – Cardiovascular

Clinical Trial Design Specialist – Cardiovascular

$190-$220 per hour

Hourly contract

United States

Posted by Mercor

mercor.com

Mercor is hiring a Clinical Trial Design Specialist on behalf of a partner at the intersection of healthcare and innovation. This role focuses on the design and development of clinical trials for cardiovascular therapeutics, with emphasis on drugs such as statins, PCSK9 inhibitors, colchicine, IL-6/IL-1B monoclonal antibodies, NLRP3 inhibitors, bempedoic acid, CETP inhibitors (e.g., obicetrapib), EPA (IPE), and Lp(a)-targeted therapies. Candidates with broader experience in trial design across therapeutic areas are also encouraged to apply.

Responsibilities

• Lead the design, protocol development, and statistical framework for Phase I–III cardiovascular and inflammatory disease trials.
• Collaborate with clinicians, regulatory experts, and biostatisticians to optimize trial endpoints, patient selection, and study power.
• Ensure compliance with FDA, EMA, and ICH guidelines for trial design and execution.
• Review and incorporate real-world evidence, biomarkers, and emerging trial methodologies into study planning.
• Support cross-functional teams in regulatory submissions, trial monitoring, and results interpretation.
• Provide expertise in risk mitigation, adaptive trial design, and innovative methodologies.

Requirements

• Advanced degree (MD, PhD, PharmD, or MSc) in Clinical Research, Medicine, or Life Sciences.
• 5+ years of experience in clinical trial design and development, with cardiovascular disease experience strongly preferred.
• Proven experience in protocol writing, endpoint selection, and regulatory interactions.
• Familiarity with biostatistics, trial modeling, and adaptive design methodologies.
• Strong understanding of drug development across small molecules, biologics, and novel therapeutics.
• Excellent collaboration, writing, and communication skills for multidisciplinary teams.

Why Join

• Shape the future of cardiovascular and inflammatory disease drug development.
• Work alongside leading clinicians, scientists, and biotech innovators.
• Influence the design of high-impact trials advancing next-generation therapies.
• Flexible engagement opportunities (consulting or full-time) with global exposure.

We consider all qualified applicants without regard to legally protected characteristics and provide reasonable accommodations upon request.