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Bioinformatics Scientist, Assay Design And Pipelines - Remote Eligible

Develop scalable bioinformatics pipelines for high-throughput assay content creation
Singapore
Mid-Level
3 days ago
Thermo Fisher

Thermo Fisher

Provides scientific instruments, reagents, software, and services enabling research, diagnostics, and manufacturing in healthcare, life sciences, and applied markets.

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Bioinformatics Scientist

We are seeking a skilled and motivated Bioinformatics Scientist to join our team, specializing in assay and content development for qPCR, dPCR, and CE technologies. The role focuses on delivering high-quality assays on schedule and contributing to the development and maintenance of computational pipelines, databases, and infrastructure to scale assay development. This position requires strong domain knowledge of genomics, PCR-based methods, and proficiency in bioinformatics pipeline development. You will convert biological questions into assay strategies and assign robust primer/probe sets. You will streamline workflows and optimize code for efficiency and scalability. Collaboration with other bioinformatics scientists, product management, and customer support colleagues is essential.

Primary Responsibilities

  • Design, develop, and optimize qPCR assays for various applications, including gene expression, genotyping, copy number analysis, and pathogen detection.
  • Analyze and interpret complex genomic and sequence data to support target selection and assay development.
  • Prepare and present scientific reports and presentations to communicate findings and progress.
  • Develop, maintain, and optimize bioinformatics pipelines and workflow automation for large-scale assay development.
  • Maintain version-controlled repositories, documentation, and reproducibility across computational workflows.
  • Participate in the publication or productization of developed algorithms, pipelines, or tools.

Required Qualifications

  • PhD or Master's degree in Bioinformatics, Computational Biology, Molecular Biology, Bioinformatics, or related fields. Preferred with 2+ years of relevant experience.
  • Strong genomics & molecular biology domain knowledge in at least one of the domains in plant, mammalian, microbial, and oncology systems.
  • Bioinformatics stack: IGV, BLAST, BWA/other aligners; major databases (GenBank, Ensembl); experience across genomics, and quantitative data with strong analytical, problem-solving skills.
  • Strong programming for scripting: advanced Python and proficient R, with additional experience in C/C++/Java/Perl/Python/JavaScript/ReactJS; solid debugging.
  • Teaming & execution: excellent communication; effective cross-functional collaboration; able to work independently and manage multiple projects concurrently.

Preferred Qualifications

  • Familiarity with machine learning or LLM-based methods or statistical methods for biological analysis.
  • Experience with other assay development platforms, such as NGS, microarrays, etc.
  • Familiarity with workflow orchestration frameworks (Nextflow, Snakemake, Latch) or cloud computing and high performance computing environments.
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Bioinformatics Scientist, Assay Design And Pipelines - Remote Eligible
Singapore
Design
About Thermo Fisher
Provides scientific instruments, reagents, software, and services enabling research, diagnostics, and manufacturing in healthcare, life sciences, and applied markets.