Scientist II, Drug Product Process And Formulation

Scientist II, Drug Product Process and Formulation

Vir Biotechnology is a clinical-stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical-stage portfolio includes programs for chronic hepatitis delta and multiple dual-masked T-cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies.

We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels supported and encouraged to give their best.

The Opportunity

Vir Biotechnology is looking for an experienced scientist II to join our Drug Product Process and Formulation group. You will be developing both liquid and lyophilized formulations for multiple modalities in biologics as well as supporting clinical stage process development and manufacturing programs. This position encompasses early and late-stage drug product development activities. The successful candidate will design and oversee formulation development for molecules both internally and with contract manufacturing organizations. You will guide the technical aspects of formulation, process development, tech transfer to manufacturing site, and scientific oversight of drug product and process data generated internally and with partner organizations.

This person will report to the Director, Drug Product Process and Formulation.

This role is located in our San Francisco headquarters with an expectation of 4 days per week in office.

What You'll Do

• Develop robust, stable, and effective parenteral formulations for monoclonal antibodies and biologics.
• Help develop the manufacturing processes for parenteral dosage forms of biologics for the clinic.
• Perform lab work in-house to support formulation, analytical and manufacturing process development activities, including execution of in-use stability studies.
• Support technical transfer of manufacturing process from development to clinical and commercial contract manufacturing organizations.
• Author technical reports, regulatory submission sections, and white papers
• Design and support clinical compatibility studies
• Collaborate with clinical, drug substance process development, analytical and quality groups to maintain project timelines
• Provide scientific oversight of formulation and process development and data generated by internal and contract labs

Who You Are and What You Bring

• Bachelor's Degree with 8+ years' experience, Master's Degree with 6+ years' experience or PhD with 3+ years in Biosciences, Pharmaceutical Technology, Biochemistry, Chemistry, Chemical Engineering, or a related discipline
• Experience with formulation and drug product development with monoclonal antibodies is required
• Experience with lyophilization and prefilled syringe development is a plus
• Experience in design of experiment (DoE) and using statistical programs
• Knowledge and familiarity with analytical methods for formulation screening of complex biological systems is preferred.
• Possess a solid understanding of pharmaceutical development, particularly as related to biological drug development
• Technical writing skills and experience authoring development reports, batch records, SOPs, regulatory filings, or other documents
• Strong written and verbal communication skills, and familiarity with representation on inter-disciplinary teams

Who We Are and What We Offer

The expected salary range for this position is $134,500 to $169,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors.

Vir Biotechnology's compensation and benefits are aligned with the current market and commensurate with the person's experience and qualifications. All full-time employees receive a package that includes compensation, bonus and equity as well as many other Vir Biotechnology benefits and perks such as health and welfare benefit plans, non-accrual paid time off, company shut down for holidays, commuter benefits, childcare reimbursement, education reimbursement, 401K match and lunch each day in the office.